Medik8 Exo-PDRN Prismatic+
Chosen to sit alongside a microneedling routine rather than replace it.
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Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex
Inspired by polynucleotide treatments, Exo-PDRN Prismatic+ has been expertly designed to deliver a multi-dimensional approach to visible skin health, boosting the skin’s natural rejuvenation by +50%[1]. Powered by intelligent prismatic PDRN, with a stable tetrahedral structure that mimics an arrow’s aerodynamic form, to allow for optimal penetration. Prismatic PDRN delivers 2x better skin absorption and 60% deeper skin penetration than traditional PDRN[4], to support skin recovery. The result? Next-generation rejuvenation for visibly enhanced luminosity and lasting resilience. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProtein™ visibly restores by supporting the skin’s natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor supports the skin’s natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
Key Benefits
- Visible Skin Rejuvenation – Scientifically proven to boost the skin’s natural rejuvenation by over 50%.[1]
- Refined Tone & Texture – Supports visibly smoother skin with improved tone and texture.
- Optimal Skin Recovery Support – Designed to support the skin’s natural recovery processes, making it ideal for daily use and alongside professional treatments.
- Restored Vitality & Luminosity – Clinically proven to improve the look of skin luminosity and vitality in 7 days.[2]
- Visibly Calm, Resilient-Looking Skin – Clinically proven to improve skin barrier function in 7 days.[2]
Proven Results
- +50% boost in natural skin rejuvenation[1]
- 7 days to improved skin barrier function[2]
- 7 days to improved skin tone[2]
- 7 days to improved skin luminosity[2]
- 7 days to visibly improved skin volume[2]
- 14 days to visibly improved wrinkles[2]
- 14 days to improved firmness[2]
- 100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment[3]
- 98% agree the results continue to get better with time[3]
[1] Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours. [2] Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 8 weeks. [3] Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study. [4] Proven via in vitro skin penetration study versus salmon and rose PDRN benchmarks.
How to Use
First-time use: If you're new to Exo-PDRN Prismatic+, we recommend a patch test at least 24 hours before first use.
How to use: After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
Key Ingredients
- Prismatic PDRN – A pioneering form of vegan (certified by The Vegan Society to be formulated without animal-derived ingredients or by-products) PDRN with a stable tetrahedral structure for 100% better skin absorption than traditional PDRN.[4] Composed of DNA particles that penetrate 61% deeper than traditional PDRN[4] to support skin recovery, help soothe visible irritation and reveal smoother, more youthful-looking skin.
- Triple Exosome Complex – Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
- GF MiniProtein™ – Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.
- ATP Precursor – An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
Full Ingredients
Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate
Measured, not promised.
Every figure here is on the device, in the box, or in our policy. Nothing is a marketing round-up.
The questions we actually get
Dr. Pen — as featured in
InStyle, Women’s Health, Cosmopolitan, Vogue.Before you buy
Using this with microneedling
Microneedling opens channels for a few hours. What you apply afterwards, and when, changes the result.










